abstract：:The aim of the present study was to assess the role of action observation treatment (AOT) in the rehabilitation of upper limb motor functions in children with cerebral palsy. We carried out a two-group, parallel randomized controlled trial. Eighteen children (aged 5-11 yr) entered the study: 11 were treated children, ...

journal_title：Neural plasticity

authors： Buccino G,Molinaro A,Ambrosi C,Arisi D,Mascaro L,Pinardi C,Rossi A,Gasparotti R,Fazzi E,Galli J

更新日期：2018-07-04 00:00:00

abstract：:Aging is a complex process strongly determined by genetics. Previous reports have shown that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy number variations (CNVs). CNVs represent a significant source of genetic variation in the human genome and have been implicated in several diso...

journal_title：Neural plasticity

authors： Villela D,Suemoto CK,Leite R,Pasqualucci CA,Grinberg LT,Pearson P,Rosenberg C

更新日期：2018-06-28 00:00:00

abstract：:Freezing of gait (FoG) is among the most disabling symptoms of Parkinson's disease (PD) patients. Recent studies showed that action observation training (AOT) with repetitive practice of the observed actions represents a strategy to induce longer-lasting effects compared with standard physiotherapy. We investigated wh...

journal_title：Neural plasticity

authors： Pelosin E,Barella R,Bet C,Magioncalda E,Putzolu M,Di Biasio F,Cerulli C,Casaleggio M,Abbruzzese G,Avanzino L

更新日期：2018-05-27 00:00:00

abstract：:Neurogenesis in the hippocampus is influenced by several factors including external stimuli. In addition to their involvement in learning and memory processes, newborn neurons of the dentate gyrus (DG) buffer against the effects of stress. Although the response of these cells to environmental stimuli has been shown, t...

journal_title：Neural plasticity

authors： Ramírez-Rodríguez GB,Ocaña-Fernández MDÁ,Ortiz-López L

更新日期：2018-05-22 00:00:00

abstract：:Neurophysiological and neuroimaging data suggest that the brains of not only children but also adults are reorganized based on sensory inputs and behaviors. Plastic changes in the brain are generally beneficial; however, maladaptive cortical reorganization in the auditory cortex may lead to hearing disorders such as t...

journal_title：Neural plasticity

authors： Okamoto H

更新日期：2018-05-20 00:00:00

abstract：Background:Parkinson's disease (PD) patients experience cognitive impairment which has been related to reduced quality of life and functional disability. These symptoms usually progress until dementia occurs. Some studies have been published assessing the efficacy of cognitive treatments on improving cognition, functio...

journal_title：Neural plasticity

authors： Díez-Cirarda M,Ibarretxe-Bilbao N,Peña J,Ojeda N

更新日期：2018-05-06 00:00:00

abstract：:Sustained activation of NLRP3 inflammasome is closely related to diabetes and stroke. However, it is unknown whether NLRP3 inflammasome plays an essential role in stroke in diabetes. We aim to investigate the effect and the potential mechanism of NLRP3 inflammasome in diabetic mice with cerebral ischemia-reperfusion i...

journal_title：Neural plasticity

authors： Hong P,Li FX,Gu RN,Fang YY,Lai LY,Wang YW,Tao T,Xu SY,You ZJ,Zhang HF

更新日期：2018-04-24 00:00:00

abstract：:Action observation (AO) allows access to a network that processes visuomotor and sensorimotor inputs and is believed to be involved in observational learning of motor skills. We conducted three consecutive experiments to examine the boosting effect of AO on the motor outcome of the untrained hand by either mirror visu...

journal_title：Neural plasticity

authors： Bähr F,Ritter A,Seidel G,Puta C,Gabriel HHW,Hamzei F

更新日期：2018-04-10 00:00:00

abstract：:Hearing impairment is one of the most common sensory disease, of which more than 50% is attributed to a genetic etiology. The goal of this research is to explore the genetic cause of a Chinese deafness pedigree who was excluded of GJB2, SLC26A4, or MtDNA12SrRNA variants. Three variants, c.3971C>A (p.A1324D), c.4011ins...

journal_title：Neural plasticity

authors： Zhang F,Xu L,Xiao Y,Li J,Bai X,Wang H

更新日期：2018-04-05 00:00:00

abstract：Background:Bilateral arm training (BAT) has shown promise in expediting progress toward upper limb recovery in chronic stroke patients, but its neural correlates are poorly understood. Objective:To evaluate changes in upper limb function and EEG power after a robot-assisted BAT in chronic stroke patients. Methods:In ...

journal_title：Neural plasticity

authors： Gandolfi M,Formaggio E,Geroin C,Storti SF,Boscolo Galazzo I,Bortolami M,Saltuari L,Picelli A,Waldner A,Manganotti P,Smania N

更新日期：2018-03-26 00:00:00

abstract：Background:Despite intensive rehabilitation efforts, most stroke survivors have persistent functional disability of the paretic arm and hand. These motor impairments may be due in part to maladaptive changes in structural and functional connections between brain regions. The following early stage clinical trial study p...

journal_title：Neural plasticity

authors： Borich MR,Wolf SL,Tan AQ,Palmer JA

更新日期：2018-03-12 00:00:00

abstract：:Neuropathic pain increases the risk of cardiovascular diseases including hypertension with the characteristic of sympathetic overactivity. The enhanced tonically active glutamatergic input to the rostral ventrolateral medulla (RVLM) contributes to sympathetic overactivity and blood pressure (BP) in cardiovascular dise...

journal_title：Neural plasticity

authors： Wang W,Zou Z,Tan X,Zhang RW,Ren CZ,Yao XY,Li CB,Wang WZ,Shi XY

更新日期：2017-01-01 00:00:00

abstract：:Although many studies have investigated the functions of histidine triad nucleotide-binding protein 1 (HINT1), its roles in neurobiological processes remain to be fully elucidated. As a member of the histidine triad (HIT) enzyme superfamily, HINT1 is distributed in almost every organ and has both enzymatic and nonenzy...

journal_title：Neural plasticity

authors： Liu P,Liu Z,Wang J,Ma X,Dang Y

更新日期：2017-01-01 00:00:00

abstract：:Emotionally arousing events are typically better remembered than mundane ones, in part because emotionally relevant aspects of our environment are prioritized in attention. Such biased attentional tuning is itself the result of associative processes through which we learn affective and motivational relevance of cues. ...

journal_title：Neural plasticity

authors： Ehlers MR,Todd RM

更新日期：2017-01-01 00:00:00

abstract：:With action video games (AVGs) becoming increasingly popular worldwide, the cognitive benefits of AVG experience have attracted continuous research attention over the past two decades. Research has repeatedly shown that AVG experience can causally enhance cognitive ability and is related to neural plasticity in gray m...

journal_title：Neural plasticity

authors： Gong D,Ma W,Gong J,He H,Dong L,Zhang D,Li J,Luo C,Yao D

更新日期：2017-01-01 00:00:00

abstract：:The role of the right hemisphere (RH) in recovery from aphasia is incompletely understood. The present study quantified RH grey matter (GM) volume in individuals with chronic stroke-induced aphasia and cognitively healthy people using voxel-based morphometry. We compared group differences in GM volume in the entire RH...

journal_title：Neural plasticity

authors： Lukic S,Barbieri E,Wang X,Caplan D,Kiran S,Rapp B,Parrish TB,Thompson CK

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to investigate the effect of subdiaphragmatic vagotomy on insulin sensitivity, secretion, and degradation in metabolic programmed mice, induced by a low-protein diet early in life, followed by exposure to a high-fat diet in adulthood. Weaned 30-day-old C57Bl/6 mice were submitted to a low-pro...

journal_title：Neural plasticity

authors： Lubaczeuski C,Gonçalves LM,Vettorazzi JF,Kurauti MA,Santos-Silva JC,Bonfleur ML,Boschero AC,Costa-Júnior JM,Carneiro EM

更新日期：2017-01-01 00:00:00

abstract：:When activated, metabotropic glutamate receptors (mGlus) exert long-lasting changes within the glutamatergic synapses. One mechanism is a tonic effect of downstream signal transduction pathways via sustained activation of mGlu itself. Like many other G protein-coupled receptors (GPCRs), mGlu can exist in a constitutiv...

journal_title：Neural plasticity

authors： Chung G,Kim SJ

更新日期：2017-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia in the elderly; important risk factors are old age and inheritance of the apolipoprotein E4 (APOE4) allele. Changes in amyloid precursor protein (APP) binding, trafficking, and sorting may be important AD causative factors. Secretase-mediated APP cleavage pr...

journal_title：Neural plasticity

authors： Zollo A,Allen Z,Rasmussen HF,Iannuzzi F,Shi Y,Larsen A,Maier TJ,Matrone C

更新日期：2017-01-01 00:00:00

abstract：:Most citizen people are exposed daily to environmental noise at moderate levels with a short duration. The aim of the present study was to determine the effects of daily short-term exposure to moderate noise on sound level processing in the auditory midbrain. Sound processing properties of auditory midbrain neurons we...

journal_title：Neural plasticity

authors： Cheng L,Wang SH,Peng K,Liao XM

更新日期：2017-01-01 00:00:00

abstract：:Synaptopathies are diseases with synapse defects as shared pathogenic features, encompassing neurodegenerative disorders such as Parkinson's disease (PD). In sporadic PD, the most common age-related neurodegenerative movement disorder, nigrostriatal dopaminergic deficits are responsible for the onset of motor symptoms...

journal_title：Neural plasticity

authors： Longhena F,Faustini G,Missale C,Pizzi M,Spano P,Bellucci A

更新日期：2017-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) is a serious medical and social problem worldwide. Because of the complex pathophysiological mechanisms of TBI, effective pharmacotherapy is still lacking. The microglial cells are resident tissue macrophages located in the brain and have two major polarization states, M1 phenotype and M2 ...

journal_title：Neural plasticity

authors： Xu H,Wang Z,Li J,Wu H,Peng Y,Fan L,Chen J,Gu C,Yan F,Wang L,Chen G

更新日期：2017-01-01 00:00:00

abstract：:The formation of the complex cerebellar cortical circuits follows different phases, with initial synaptogenesis and subsequent processes of refinement guided by a variety of mechanisms. The regularity of the cellular and synaptic organization of the cerebellar cortex allowed detailed studies of the structural plastici...

journal_title：Neural plasticity

authors： Hoxha E,Lippiello P,Scelfo B,Tempia F,Ghirardi M,Miniaci MC

更新日期：2017-01-01 00:00:00

abstract：:Several studies have associated reduced expression of synaptosomal-associated protein of 25 kDa (SNAP-25) with schizophrenia, yet little is known about its role in the illness. In this paper, a forebrain glutamatergic neuron-specific SNAP-25 knockout mouse model was constructed and studied to explore the possible path...

journal_title：Neural plasticity

authors： Yang H,Zhang M,Shi J,Zhou Y,Wan Z,Wang Y,Wan Y,Li J,Wang Z,Fei J

更新日期：2017-01-01 00:00:00

abstract：:Major depressive disorder is a severe and complex mental disorder. Impaired neurotransmission and disrupted signalling pathways may influence neuroplasticity, which is involved in the brain dysfunction in depression. Traditional neurobiological theories of depression, such as monoamine hypothesis, cannot fully explain...

journal_title：Neural plasticity

authors： Huang YJ,Lane HY,Lin CH

更新日期：2017-01-01 00:00:00

abstract：:We do not all grow older in the same way. Some individuals have a cognitive decline earlier and faster than others who are older in years but cerebrally younger. This is particularly easy to verify in people who have maintained regular physical activity and healthy and cognitively stimulating lifestyle and even in the...

journal_title：Neural plasticity

authors： Mandolesi L,Gelfo F,Serra L,Montuori S,Polverino A,Curcio G,Sorrentino G

更新日期：2017-01-01 00:00:00

abstract：:The formation of fear memories is a powerful and highly evolutionary conserved mechanism that serves the behavioral adaptation to environmental threats. Accordingly, classical fear conditioning paradigms have been employed to investigate fundamental molecular processes of memory formation. Evidence suggests that a cir...

journal_title：Neural plasticity

authors： Albrecht A,Stork O

更新日期：2017-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/6724631.]. ...

journal_title：Neural plasticity

authors： Binda P,Lunghi C

更新日期：2017-01-01 00:00:00

abstract：:Although quantitative analysis of the sleep electroencephalogram (EEG) has uncovered important aspects of brain activity during sleep in adolescents and adults, similar findings from preschool-age children remain scarce. This study utilized our time-frequency method to examine sleep oscillations as characteristic feat...

journal_title：Neural plasticity

authors： Olbrich E,Rusterholz T,LeBourgeois MK,Achermann P

更新日期：2017-01-01 00:00:00

abstract：:Cholinergic mechanism is involved in motor behavior. In songbirds, the robust nucleus of the arcopallium (RA) is a song premotor nucleus in the pallium and receives cholinergic inputs from the basal forebrain. The activity of projection neurons in RA determines song motor behavior. Although many evidences suggest that...

journal_title：Neural plasticity

authors： Meng W,Wang SH,Li DF

更新日期：2016-01-01 00:00:00

abstract：:Autosomal dominant nonsyndromic hearing loss (ADNSHL) is extremely heterogeneous. So far the genetic etiological contribution of the gene POU4F3 associated with ADNSHL has been rarely reported. In our previous study, a c.603_604delGG mutation in the hair cell specific gene POU4F3 has been identified as the pathogenic ...

journal_title：Neural plasticity

authors： He L,Pang X,Chen P,Wu H,Yang T

更新日期：2016-01-01 00:00:00

abstract：:Measurement of sleep microarchitecture and neural oscillations is an increasingly popular technique for quantifying EEG sleep activity. Many studies have examined sleep spindle oscillations in sleep-disordered adults; however reviews of this literature are scarce. As such, our overarching aim was to critically review ...

journal_title：Neural plasticity

authors： Weiner OM,Dang-Vu TT

更新日期：2016-01-01 00:00:00

abstract：:Objective. To explore cortical reorganization of patients recovered from Bell's palsy (BP) by task-state functional magnetic resonance imaging (fMRI) during finger and orofacial movements and provide more evidence for acupuncture clinical treatment of BP. Methods. We collected 17 BP patients with complete clinical rec...

journal_title：Neural plasticity

authors： Lee J,Yang J,Li C,Yuan A,Wu H,Wang A,Xue Q,Wang T,Wang L,Gao T

更新日期：2016-01-01 00:00:00

abstract：:Histamine H4 receptor has been confirmed to play a role in evoking peripheral pruritus. However, the ionic and intracellular signaling mechanism of activation of H4 receptor on the dorsal root ganglion (DRG) neurons is still unknown. By using cell culture and calcium imaging, we studied the underlying mechanism of act...

journal_title：Neural plasticity

authors： Jian T,Yang N,Yang Y,Zhu C,Yuan X,Yu G,Wang C,Wang Z,Shi H,Tang M,He Q,Lan L,Wu G,Tang Z

更新日期：2016-01-01 00:00:00

abstract：:Proper density and morphology of dendritic spines are important for higher brain functions such as learning and memory. However, our knowledge about molecular mechanisms that regulate thedevelopment and maintenance of dendritic spines is limited. We recently reported that cyclin-dependent kinase 5 (Cdk5) is required f...

journal_title：Neural plasticity

authors： Jin X,Sasamoto K,Nagai J,Yamazaki Y,Saito K,Goshima Y,Inoue T,Ohshima T

更新日期：2016-01-01 00:00:00

abstract：:Associative fear learning, in which stimulation of whiskers is paired with mild electric shock to the tail, modifies the barrel cortex, the functional representation of sensory receptors involved in the conditioning, by inducing formation of new inhibitory synapses on single-synapse spines of the cognate barrel hollow...

journal_title：Neural plasticity

authors： Jasinska M,Siucinska E,Jasek E,Litwin JA,Pyza E,Kossut M

更新日期：2016-01-01 00:00:00

abstract：:Perinatal stroke is a leading cause of congenital hemiparesis and neurocognitive deficits in children. Dysfunctions in the large-scale resting-state functional networks may underlie cognitive and behavioral disability in these children. We studied resting-state functional connectivity in patients with perinatal stroke...

journal_title：Neural plasticity

authors： Ilves N,Ilves P,Laugesaar R,Juurmaa J,Männamaa M,Lõo S,Loorits D,Tomberg T,Kolk A,Talvik I,Talvik T

更新日期：2016-01-01 00:00:00

abstract：:Previous studies have demonstrated that amnestic mild cognitive impairment (aMCI) has disrupted properties of large-scale cortical networks based on cortical thickness and gray matter volume. However, it is largely unknown whether the topological properties of cortical networks based on geometric measures (i.e., sulca...

journal_title：Neural plasticity

authors： Li Q,Li X,Wang X,Li Y,Li K,Yu Y,Yin C,Li S,Han Y

更新日期：2016-01-01 00:00:00

abstract：:The development of new strategies to renew and repair neuronal networks using neural plasticity induced by stem cell graft could enable new therapies to cure diseases that were considered lethal until now. In adequate microenvironment a neuronal progenitor must receive molecular signal of a specific cellular context t...

journal_title：Neural plasticity

authors： Ramírez-Barrantes R,Cordova C,Poblete H,Muñoz P,Marchant I,Wianny F,Olivero P

更新日期：2016-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia in elderly people. It is an irreversible and progressive brain disease. In this paper, we utilized diffusion-weighted imaging (DWI) to detect abnormal topological organization of white matter (WM) structural networks. We compared the differences between WM c...

journal_title：Neural plasticity

authors： Wang T,Shi F,Jin Y,Yap PT,Wee CY,Zhang J,Yang C,Li X,Xiao S,Shen D

更新日期：2016-01-01 00:00:00